Types of Hormonal Therapy: What You Need to Know

Hormonal therapy (HT) is not only an effective but also often essential treatment to maintain the normal functioning of the body. However, despite its importance, many women fear this form of treatment, worrying about potential side effects. In this article, we will review the main types of hormonal therapy and their indications, as well as discuss how to choose the correct dosage for different situations.

What is Hormonal Therapy?

Hormonal therapy involves the use of synthetic or artificially synthesized hormones to restore normal hormone levels in the body. Depending on the indications, HT can be prescribed for either a short or long duration.

Hormone Replacement Therapy (HRT)

The first type of hormonal therapy is hormone replacement therapy (HRT). This is necessary when there is a hormone deficiency or disruption in hormone production. This can occur due to the removal of an endocrine organ, such as the thyroid gland. In such cases, patients require continuous intake of thyroxine to normalize metabolic processes.

• Example: After thyroid removal, patients are prescribed thyroxine to compensate for the hormone deficiency.
• Goal: To find the minimum effective dose to support normal bodily functions without the risk of overdose.

Adjusting Dosage in HRT

Adjusting the hormone dosage takes time as the body needs to adapt. Periodic hormone level testing in the blood helps doctors fine-tune the dosage and achieve the optimal level.

Premature Ovarian Failure and Hormone Replacement

In women who have had their ovaries removed or experienced premature ovarian failure, there is a deficiency in estradiol. In these cases, hormone replacement therapy becomes vital to prevent menopause symptoms and other hormone deficiency-related diseases.

Treating Acute Conditions with Hormones

The second type of hormonal therapy is the use of hormones in emergency situations. This is used for rapid relief in acute illnesses, such as allergic reactions, anaphylactic shock, or inflammatory processes. In such cases, glucocorticoids are often used in high doses, which can quickly address life-threatening conditions.

• Example: Treating anaphylactic shock with glucocorticoids to prevent the patient's death.
• Drawbacks: Long-term use of high doses may lead to side effects such as weight gain or metabolic disorders.

Side Effects and Risks

The main side effects of hormonal therapy, particularly with high doses, include weight gain and metabolic issues. However, when hormones are prescribed correctly, as in hormone replacement therapy, side effects are minimal and do not lead to significant changes in the body.

Conclusion

Hormonal therapy is an important and necessary treatment for various diseases and conditions related to hormonal imbalances. Whether it’s hormone replacement or treating acute conditions, proper prescription and dosage control are key to a successful outcome.

Important: Do not stop hormone treatment without consulting your doctor. Self-discontinuation of medication may lead to deterioration of your condition and the development of new symptoms.